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APA
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Health, Medicine, Nursing
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English (U.S.)
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Topic:

Lentigo Melanomas

Other (Not Listed) Instructions:

Answer all of the questions below using the "Discussion Forum Sample" for your discussion response.
History
R.S. is a 38-year-old white male who presents to his PCP after his wife noticed a suspicious-looking, dark brown mole in his scalp while giving him a haircut. He was referred to your clinic. He has a history of lipoma over the left ribcage, surgically removed 10 years ago with no recurrence. He reports an episode of major depression with suicidal tendencies eight years ago, treated successfully with an antidepressant and psychotherapy for 10 weeks with no recurrence.
ROS
No changes in vision, smell, or hearing.
No headaches, cough, fever, chills, night sweats, nausea, or vomiting.
No changes in bowel or bladder habits.
No fatigue or weakness.
SKIN
Fair complexion with multiple scattered nevi on the back.
Negative for rashes and other lesions.
Warm to the touch and slightly diaphoretic.
Normal distribution of body hair.
HEENT
7-mm nodule on the scalp above the right ear, dome-shaped, symmetric, dark brown in color, no variations.
PERRLA.
EOMI.
Funduscopic WNL.
Normal sclera.
TMs intact.
Mucous membranes moist.
Throat without lesions, edema, exudates, or erythema.
Poor dentition, several fractured teeth.
Biopsy
An excisional biopsy of the mole showed cells consistent with that of nodular melanoma. Tumor thickness was 3.8 mm. Cervical nodes were enlarged and measured 2.3 and 2.7 cm. A CT scan of the thorax was negative. With the exception of questionable shadows in the liver, the abdominal CT scan was also negative. A CT scan of the brain was clearly positive for 3 lesions.
Laboratory Blood Test Results
Na = 142 meq/L
Cr = 0.6 mg/dL
WBC = 7,200/mm3
AST = 115 IU/L
K = 4.5 meq/L
RBC = 5.3 million/mm3
ALT = 145 IU/L
Hct = 43%
Glu, fasting = 103 mg/dL
Mg = 2.7 mg/dL
HCO3 = 31 meq/L
Cl = 103 meq/L
Bilirubin, total = 1.7 mg/dL
PO4 = 4.4 mg/dL
Ca = 10.3 mg/dL
BUN = 14 mg/dL
Alb = 3.5 g/dL
Alk phos = 278 IU/L
Plt = 239,000/mm3
Hb = 16.3 g/dL
Questions
Why is the lack of clinical manifestations in the ROS above significant?
Based on this rather limited information provided under History, ROS, SKIN, and HEENT above, which subtype of melanoma is most likely?
Are any of the laboratory blood test results above abnormal and, if so, what is suggested by the abnormality?
What is the current probability that this patient will be alive in 10 years?

Other (Not Listed) Sample Content Preview:

Week 14 DQ 1
Student’s Name
University Affiliation
Professor’s Name
Course Title
Due Date
Week 14 DQ 1: Melanoma
The lack of clinical manifestations in the review of systems is significant as it helps to rule out several other differential diagnoses of melanoma. It helps by creating specific concentration and focus on the clinical attributes of melanoma. Based on the information provided on the patient medical history, review of systems, skin, hair, ear, eye, nose, and throat evaluation, the melanoma subtype that is likely to be is lentigo melanoma.
Lentigo melanoma begins to form on the top layer of the skin and later invades the deeper skin layers. It usually occurs mainly on the face, neck, and ears in older adults (Apalla et al., 2017). Lentigo melanomas can be confused for benign tumors as they take a long time to spread. Based on the patient's history, he had a lipoma ten years ago, and this current m...
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